schemadotorg_starterkit_medical-1.0.x-dev/modules/schemadotorg_starterkit_medical_default_content/content/node/cb751c50-5a19-49d7-bac4-a236812cddcd.yml

_meta:
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  entity_type: node
  uuid: cb751c50-5a19-49d7-bac4-a236812cddcd
  bundle: medical_condition
  default_langcode: en
  depends:
    4e9ba4cb-1bb0-45d2-8d2a-a4e914253c3b: node
    4af3743c-9365-4e2b-9361-65310fd96635: node
    886512f9-8e7d-4c57-baa0-25c1827e7f54: node
default:
  revision_uid:
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      target_id: 1
  revision_log:
    -
      value: 'Updated the Metatags (Hidden field for JSON support), Editorial information, and Health aspects fields'
  status:
    -
      value: true
  uid:
    -
      target_id: 1
  title:
    -
      value: 'Breast cancer'
  created:
    -
      value: 1714473542
  promote:
    -
      value: true
  sticky:
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      value: false
  revision_translation_affected:
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      value: true
  moderation_state:
    -
      value: published
  metatag:
    -
      tag: meta
      attributes:
        name: title
        content: 'Breast cancer | Schema.org Blueprints Demo'
    -
      tag: meta
      attributes:
        name: description
        content: 'Breast cancer is a cancer that develops from breast tissue.[7] Signs of breast cancer may include a lump in the breast, a change in breast shape, dimpling of the skin, milk rejection, fluid coming from the'
    -
      tag: meta
      attributes:
        name: robots
        content: robots
    -
      tag: link
      attributes:
        rel: canonical
        href: 'https://schemadotorg.ddev.site/medical/conditions/breast-cancer'
    -
      tag: meta
      attributes:
        property: 'og:url'
        content: 'https://schemadotorg.ddev.site/medical/conditions/breast-cancer'
    -
      tag: meta
      attributes:
        property: 'og:title'
        content: 'Breast cancer'
    -
      tag: meta
      attributes:
        property: 'og:description'
        content: 'Breast cancer is a cancer that develops from breast tissue.[7] Signs of breast cancer may include a lump in the breast, a change in breast shape, dimpling of the skin, milk rejection, fluid coming from the'
    -
      tag: meta
      attributes:
        property: 'og:video:type'
        content: movie
    -
      tag: meta
      attributes:
        property: 'og:updated_time'
        content: '2024-05-16T14:43:43+0000'
    -
      tag: meta
      attributes:
        property: 'article:modified_time'
        content: '2024-05-16T14:43:43+0000'
    -
      tag: meta
      attributes:
        name: 'twitter:title'
        content: 'Breast cancer'
    -
      tag: meta
      attributes:
        name: 'twitter:description'
        content: 'Breast cancer is a cancer that develops from breast tissue.[7] Signs of breast cancer may include a lump in the breast, a change in breast shape, dimpling of the skin, milk rejection, fluid coming from the'
  path:
    -
      alias: /medical/conditions/breast-cancer
      langcode: en
      pathauto: 1
  field_editorial:
    -
      entity:
        _meta:
          version: '1.0'
          entity_type: paragraph
          uuid: c25e3c67-1b23-4095-a1c4-1462c1e9270a
          bundle: editorial
          default_langcode: en
        default:
          status:
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              value: true
          created:
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              value: 1714473578
          behavior_settings:
            -
              value: {  }
  field_metatag:
    -
      value: '{"robots":"robots"}'
  schema_cm_documentation:
    -
      markup: ''
  body:
    -
      value: '<p><strong>Breast cancer</strong> is a <a href="https://en.wikipedia.org/wiki/Cancer">cancer</a> that develops from <a href="https://en.wikipedia.org/wiki/Breast">breast</a> tissue.<a href="https://en.wikipedia.org/wiki/Breast_cancer#cite_note-7"><sup>[7]</sup></a> Signs of breast cancer may include a <a href="https://en.wikipedia.org/wiki/Breast_lump">lump</a> in the breast, a change in breast shape, <a href="https://en.wikipedia.org/wiki/Dimpling">dimpling</a> of the skin, <a href="https://en.wikipedia.org/wiki/Milk-rejection_sign">milk rejection</a>, fluid coming from the <a href="https://en.wikipedia.org/wiki/Nipple">nipple</a>, a newly inverted nipple, or a red or scaly patch of skin.<a href="https://en.wikipedia.org/wiki/Breast_cancer#cite_note-NCI2014Pt-1"><sup>[1]</sup></a> In those with <a href="https://en.wikipedia.org/wiki/Metastatic_breast_cancer">distant spread of the disease</a>, there may be <a href="https://en.wikipedia.org/wiki/Bone_pain">bone pain</a>, swollen <a href="https://en.wikipedia.org/wiki/Lymph_node">lymph nodes</a>, <a href="https://en.wikipedia.org/wiki/Shortness_of_breath">shortness of breath</a>, or <a href="https://en.wikipedia.org/wiki/Yellow_skin">yellow skin</a>.<a href="https://en.wikipedia.org/wiki/Breast_cancer#cite_note-8"><sup>[8]</sup></a></p>'
      format: full_html
      summary: ''
  schema_expected_prognosis:
    -
      value: 'Five-year survival rate is approximately 85% (US, UK)'
  schema_has_health_aspect:
    -
      value: CausesHealthAspect
    -
      value: LivingWithHealthAspect
    -
      value: MisconceptionsHealthAspect
    -
      value: OverviewHealthAspect
    -
      value: PatientExperienceHealthAspect
    -
      value: PreventionHealthAspect
    -
      value: PrognosisHealthAspect
    -
      value: ScreeningHealthAspect
    -
      value: StagesHealthAspect
    -
      value: SymptomsHealthAspect
    -
      value: TreatmentsHealthAspect
  schema_has_part:
    -
      entity: 4e9ba4cb-1bb0-45d2-8d2a-a4e914253c3b
    -
      entity: 4af3743c-9365-4e2b-9361-65310fd96635
    -
      entity: 886512f9-8e7d-4c57-baa0-25c1827e7f54
  schema_natural_progression:
    -
      value: 'Metastatic disease'
  schema_pathophysiology:
    -
      value: '<p>The major causes of sporadic breast cancer are associated with hormone levels. Breast cancer is promoted by estrogen. This hormone activates the development of breast throughout puberty, menstrual cycles and pregnancy. The imbalance between estrogen and progesterone during the menstrual phases causes cell proliferation. Moreover, oxidative metabolites of estrogen can increase DNA damage and mutations. Repeated cycling and the impairment of repair process can transform a normal cell into pre-malignant and eventually malignant cell through mutation. During the premalignant stage, high proliferation of stromal cells can be activated by estrogen to support the development of breast cancer. During the ligand binding activation, the ER can regulate gene expression by interacting with estrogen response elements within the promotor of specific genes. The expression and activation of ER due to lack of estrogen can be stimulated by extracellular signals.<a href="https://en.wikipedia.org/wiki/Breast_cancer#cite_note-133"><sup>[133]</sup></a> Interestingly, the ER directly binding with the several proteins, including growth factor receptors, can promote the expression of genes related to cell growth and survival.<a href="https://en.wikipedia.org/wiki/Breast_cancer#cite_note-134"><sup>[134]</sup></a></p>'
      format: full_html
  schema_possible_complication:
    -
      value: 'Metastatic cancer'
  schema_possible_treatment:
    -
      value: Surgery
    -
      value: 'Radiation therapy'
    -
      value: Chemotherapy
    -
      value: 'Hormonal therapy'
    -
      value: 'Targeted therapy'
  schema_primary_prevention:
    -
      value: Lifestyle
  schema_risk_factor:
    -
      value: 'Being female'
    -
      value: Obesity
    -
      value: 'Lack of exercise'
    -
      value: Alcohol
    -
      value: 'Hormone replacement therapy during menopause'
    -
      value: 'Ionizing radiation'
    -
      value: 'Early age at first menstruation'
    -
      value: 'Having children late in life or not at all'
    -
      value: 'Older age'
    -
      value: 'Prior breast cancer'
    -
      value: 'Family history of breast cancer'
    -
      value: 'Klinefelter syndrome'
  schema_same_as:
    -
      uri: 'https://en.wikipedia.org/wiki/Breast_cancer'
      title: 'https://en.wikipedia.org/wiki/Breast_cancer'
      options:
        href: 'https://en.wikipedia.org/wiki/Breast_cancer'
        data-entity-type: ''
        data-entity-uuid: ''
        data-entity-substitution: ''
  schema_secondary_prevention:
    -
      value: 'Preventive surgery'
    -
      value: Medications
  schema_sign_or_symptom:
    -
      value: 'A lump in a breast'
    -
      value: 'A change in breast shape'
    -
      value: 'Dimpling of the skin'
    -
      value: 'Fluid from the nipple'
    -
      value: 'A newly inverted nipple'
    -
      value: 'A red scaly patch of skin on the breast'
  schema_significant_link:
    -
      uri: 'https://www.cancer.gov/types/breast'
      title: 'Breast Cancer—Patient Version - NCI'
      options:
        href: 'https://www.cancer.gov/types/breast'
        data-entity-type: ''
        data-entity-uuid: ''
        data-entity-substitution: ''
  schema_subject_of:
    -
      entity: 4e9ba4cb-1bb0-45d2-8d2a-a4e914253c3b
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      entity: 4af3743c-9365-4e2b-9361-65310fd96635
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      entity: 886512f9-8e7d-4c57-baa0-25c1827e7f54
  schema_typical_test:
    -
      value: 'Tissue biopsy'
    -
      value: Mammography